Stressful life events across the lifespan and inflammation: An integrative data analysis.
Abstract
Experiencing more stressful life events has been linked to higher levels of inflammation, but this association may depend on when in the lifespan the stressors occur. To address this knowledge gap, we tested two lifespan theories, the accumulation of risks and sensitive period models, by assessing the association between the total number of stressful events and their life stage occurrence on later-life C-reactive protein (CRP). We harmonized data across two cohort studies, maximizing variation in stressors reported across the lifespan. Participants (N
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Research summary
The paper investigates the relationship between stressful life events and inflammation, specifically looking at how these stressors across the lifespan may influence later-life health outcomes, such as C-reactive protein levels. While it touches on factors that could contribute to aging-related inflammation, it does not directly address root causes of aging or lifespan extension. The findings may provide useful insights into the role of stress in aging, but the overall impact on the field of longevity research is limited.
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