Longitudinal Changes in Epigenetic Age Acceleration Across Childhood and Adolescence.
Abstract
Individuals exposed to discrimination may exhibit greater epigenetic age acceleration (ie, cellular indicators of premature aging) over time, but few studies have examined longitudinal changes in epigenetic age acceleration, the heterogeneity in these changes for diverse groups of youths, and contextual explanations (ie, discrimination) for differences by ethnicity or race.
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Research summary
The paper examines longitudinal changes in epigenetic age acceleration, which is directly related to the biological processes of aging. It explores the impact of discrimination on epigenetic markers, providing insights into how social factors may influence aging at a cellular level. However, while the findings may contribute to understanding the complexities of aging, they do not present a significant breakthrough or novel approach to addressing the root causes of aging or lifespan extension. Thus, the impact is rated as solid but limited.
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