Characterizing vascular and hormonal changes in women across the life span: a cross-sectional analysis.

Megan M Wenner, Ninette Shenouda, Leena Shoemaker, Andrew Kuczmarski, Katherine Haigh, Angelica Del Vecchio, Allyson Schwab, Shane J McGinty, David G Edwards, Ryan T Pohlig, Virginia R Nuckols, Lyndsey DuBose, Kerrie L Moreau

Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States. · pubmed

Paper

Abstract

Vascular dysfunction, marked by lower endothelial function and increased aortic stiffness, is a nontraditional risk factor that precedes the development of cardiovascular disease (CVD). However, the age at which these changes in vascular function occur in women and the degree to which reproductive hormones mediate these changes has not been characterized. Women free from major disease were enrolled across the adult life span (aged 18-70 yr,

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates vascular and hormonal changes in women across their lifespan, focusing on how these changes may relate to cardiovascular disease. While it addresses important aspects of aging and vascular health, it primarily describes associations rather than exploring root causes of aging or interventions that could extend lifespan. Thus, it contributes solid research but has limited impact on the broader field of longevity research.

Author of this paper? Send a correction.