Research on the mechanism of buyang huanwu decoction in the amelioration of age-associated memory impairment based on the "co-occurrence network regulation of intestinal microecology-host metabolism-immune function".

Caiyan Liu, Jieyong Du, Ji Yang, Jianhua Li, Tong Zhou, Jiaming Yu, Xiao Wang, Jiazi Lin, Yefang Liang, Ruixiang Shi, Rongfeng Luo, Xuejuan Shen, Yi Wang, Li Zhang, Zunpeng Shu

Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, 519087, China; School of Chinese Materia Medica, Guangdong Pharmaceutical University, Guangzhou, 510006, China. · pubmed

Paper

Abstract

Brain aging can promote neuronal damage, contributing to aging-related diseases like memory dysfunction. Buyang Huanwu Decoction (BYHWD), a traditional Chinese medicine formula known for tonifying qi and activating blood circulation, shows neuroprotective properties. Despite this, the specific mechanism by which BYHWD improves age-associated memory impairment (AAMI) has not been explored in existing literature.

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Research summary

The paper investigates the mechanism by which Buyang Huanwu Decoction ameliorates age-associated memory impairment. This research is relevant as it explores potential interventions targeting the underlying mechanisms of cognitive decline associated with aging.

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