Accelerated Phenotypic Aging Associated With Hepatitis C Infection: Results From the U.S. National Health and Nutrition Examination Surveys 2015-2018.
Abstract
Chronic hepatitis C virus (HCV) infection is associated with early onset of chronic diseases and increased risk of chronic disorders. Chronic viral infections have been linked to accelerated biological aging based on epigenetic clocks. In this study, we aimed to investigate the association between HCV infection and clinical measures of biological aging among 8 306 adults participating in the 2015-2018 waves of the National Health and Nutrition Examination Survey (NHANES).
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Research summary
The paper investigates the association between chronic hepatitis C infection and accelerated biological aging, which is relevant to understanding the mechanisms of aging and age-related diseases. However, while it contributes to the knowledge of how chronic infections may influence biological aging, it does not address root causes of aging or propose interventions for lifespan extension. Thus, its impact is solid but limited.
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