Age-related structural remodelling of the coronary circulation.

Daniel Faria, Marco Lombardi, Nina van der Hoeven, Alejandro Travieso, Julius C Heemelaar, Sukhjinder S Nijjer, Hernán Mejía-Rentería, Guus A de Waard, Sayan Sen, Tim P van de Hoef, Ricardo Petraco, Mauro Echavarría-Pinto, Jan J Piek, Justin E Davies, Niels van Royen, Javier Escaned

Hospital Clínico San Carlos IDISSC, Complutense University of Madrid and CIBERCV, Madrid, Spain.Hospital Clínico San Carlos IDISSC, Complutense University of Madrid and CIBERCV, Madrid, Spain. · pubmed

Paper

Abstract

While it is broadly accepted that ageing is associated with impairment of coronary microvascular function, little is known about the underlying mechanisms.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper addresses age-related structural changes in the coronary circulation, which is relevant to understanding the mechanisms of aging and how they affect cardiovascular health. However, while it contributes to the knowledge of microvascular function in aging, it does not propose solutions to the root causes of aging or lifespan extension, limiting its overall impact.

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