Socioeconomic status across the early life course predicts gene expression signatures of disease and senescence.
Abstract
Socioeconomic status (SES) is associated with many chronic diseases, indicators of senescence and mortality. However, the changing salience of SES in the prediction of adult health is not well understood. Using mRNA-seq abundance data from wave V of the National Longitudinal Study of Adolescent to Adult Health (Add Health), we examine the extent to which SES across the early life course is related to gene expression-based signatures for chronic diseases, senescence and inflammation in the late 30s.
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Research summary
The paper investigates the relationship between socioeconomic status across the early life course and gene expression signatures related to chronic diseases and senescence. While it touches on factors that may influence aging and health outcomes, it primarily focuses on correlations rather than addressing the root causes of aging or proposing interventions for lifespan extension. The findings may contribute to understanding health disparities but do not significantly advance the field of longevity research.
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