Association of accelerated biological aging with brain volumes: A cross-sectional study.

Chen Liu, Qingqing Cai, Yifan Gou, Ye Liu, Meijuan Kang, Jingni Hui, Ruixue Zhou, Panxing Shi, Bingyi Wang, Feng Zhang

Key Laboratory of Environment and Endemic Diseases of National Health Commission of China, Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education of China, Key Laboratory for Prevention and Control and Health Promotion of Shaanxi Province, School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.Key Laboratory of Environment and Endemic Diseases of National Health Commission of China, Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education of China, Key Laboratory for Prevention and Control and Health Promotion of Shaanxi Province, School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China. · pubmed

Paper

Abstract

Multiple epidemiological studies have observed the connection between aging and brain volumes. The concept of accelerated biological aging (BA) is more powerful for observing the degree of aging of an individual than chronologic age (CA). The objective of this study is to explore the relationship between BA and brain volumes.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper explores the relationship between accelerated biological aging and brain volumes, which is pertinent to understanding the biological mechanisms of aging. However, it primarily focuses on observational data rather than addressing root causes or interventions that could extend lifespan or mitigate aging effects. Thus, while it contributes to the field, its impact is limited and more incremental than transformative.

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