Marine peptides as potential anti-aging agents: Preparation, characterization, mechanisms of action, and future perspectives.
Abstract
Aging is a universal biological process characterized by a decline in physiological functions, leading to increased susceptibility to diseases. With global aging trends, understanding and mitigating the aging process is paramount. Recent studies highlight marine peptides as promising bioactive substances with potential anti-aging properties. This review critically examines the potential of marine peptides as novel food ingredients in anti-aging, exploring their sources, preparation methods, physicochemical properties, and the underlying mechanisms through which they impact the aging process. Marine peptides exhibit significant potential in targeting aging, extending lifespan, and enhancing healthspan. They act through mechanisms such as reducing oxidative stress and inflammation, modulating mitochondrial dysfunction, inducing autophagy, maintaining extracellular matrix homeostasis, and regulating longevity-related pathways. Despite challenges in stability, bioavailability, and scalability, marine peptides offer significant potential in health, nutraceuticals, and pharmaceuticals, warranting further research and development in anti-aging.
The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.
Research summary
The paper discusses marine peptides as potential anti-aging agents, focusing on their mechanisms of action and implications for healthspan and lifespan extension. This aligns with the goal of addressing the root causes of aging rather than merely treating age-related diseases. However, while the review presents a solid overview of the topic, it does not introduce groundbreaking findings or novel methodologies that would significantly advance the field, thus warranting a moderate impact score.
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