Significance of eGFR and proteinuria for cardiovascular disease in individuals beyond 85 years of age.

Tatsuhiko Azegami, Hidehiro Kaneko, Akira Okada, Yuta Suzuki, Katsuhito Fujiu, Hiroyuki Morita, Norifumi Takeda, Norihiko Takeda, Akira Fukui, Takashi Yokoo, Koichi Node, Hideo Yasunaga, Masaomi Nangaku, Kaori Hayashi

Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan. · pubmed

Paper

Abstract

There are limited data on how advancing age influences prediction of cardiovascular disease (CVD) risk based on the estimated glomerular filtration rate (eGFR) and proteinuria, especially in older adults, including those aged ≥85 years old. This study aimed to clarify the association of eGFR and proteinuria with CVD outcomes and the impact of age on this association.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the association of eGFR and proteinuria with cardiovascular disease outcomes in individuals aged 85 and older, which is pertinent to understanding health risks in the aging population. However, it primarily focuses on risk factors rather than addressing the root causes of aging or lifespan extension. The findings may contribute to the field of gerontology but do not represent a significant advancement in longevity research. Thus, the impact is rated as solid but limited.

Author of this paper? Send a correction.