The effects of omega-3 polyunsaturated fatty acids on muscle and whole-body protein synthesis: a systematic review and meta-analysis.

Atiporn Therdyothin, Konstantinos Prokopidis, Francesco Galli, Oliver C Witard, Masoud Isanejad

Department of Musculoskeletal and Ageing Science, University of Liverpool, Liverpool, L7 8TX, United Kingdom.Department of Musculoskeletal and Ageing Science, University of Liverpool, Liverpool, L7 8TX, United Kingdom. · pubmed

Paper

Abstract

Sarcopenia describes the age-related decline in skeletal muscle mass and strength that is driven, at least in part, by an imbalance between rates of muscle protein synthesis (MPS) and muscle protein breakdown. An expanding body of literature has examined the effect of omega-3 polyunsaturated fatty acid (n-3 PUFA) ingestion on MPS rates in older adults, with mixed findings.

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Research summary

The paper claims that omega-3 polyunsaturated fatty acids can positively influence muscle protein synthesis in older adults. This research is relevant as it addresses sarcopenia, a significant age-related condition that affects longevity and quality of life in the elderly.

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