Exploring the associations between skeletal muscle echogenicity and physical function in aging adults: A systematic review with meta-analyses.

Dustin J Oranchuk, Stephan G Bodkin, Katie L Boncella, Michael O Harris-Love

Muscle Morphology, Mechanics, and Performance Laboratory, Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address: [email protected] Morphology, Mechanics, and Performance Laboratory, Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address: [email protected]. · pubmed

Paper

Abstract

Assessment and quantification of skeletal muscle within the aging population is vital for diagnosis, treatment, and injury/disease prevention. The clinical availability of assessing muscle quality through diagnostic ultrasound presents an opportunity to be utilized as a screening tool for function-limiting diseases. However, relationships between muscle echogenicity and clinical functional assessments require authoritative analysis. Thus, we aimed to (a) synthesize the literature to assess the relationships between skeletal muscle echogenicity and physical function in older adults (≥60 years), (b) perform pooled analyses of relationships between skeletal muscle echogenicity and physical function, and (c) perform sub-analyses to determine between-muscle relationships.

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Research summary

The paper addresses the relationship between skeletal muscle echogenicity and physical function in older adults, which is pertinent to understanding aspects of aging and physical decline. However, it primarily focuses on assessment methods rather than addressing the root causes of aging or proposing interventions for lifespan extension. The findings may contribute to the field of gerontology but do not represent a significant advancement or breakthrough in longevity research.

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