Crosstalk between endothelial cells and dermal papilla entails hair regeneration and angiogenesis during aging.

Siyi Zhou, Zeming Li, Xinzhu Li, Yuanli Ye, Mengyue Wang, Jingwei Jiang, Lihe Tao, Yan Wang, Chen-Tsen Tung, Yongji Chung, Eunmi Kim, Xinyu Shen, Xuegang Xu, Xiao Xiang, Qiaoli Xie, Jinwei Zhang, Wang Wu, Xia Lin, Cheng-Ming Chuong, Mingxing Lei

Key Laboratory of Biorheological Science and Technology of Ministry of Education & 111 Project Laboratory of Biomechanics and Tissue Repair, College of Bioengineering, Chongqing University, Chongqing 400044, China. Electronic address: [email protected]. · pubmed

Paper

Abstract

Tissues maintain their function through interaction with microenvironment. During aging, both hair follicles and blood vessels (BV) in skin undergo degenerative changes. However, it is elusive whether the changes are due to intrinsic aging changes in hair follicles or blood vessels respectively, or their interactions.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that the interaction between endothelial cells and dermal papilla is crucial for hair regeneration and angiogenesis during aging. This research is relevant as it explores the mechanisms underlying aging-related changes in hair follicles and blood vessels, potentially addressing root causes of age-related degeneration.

Author of this paper? Send a correction.