Achieving healthy aging through gut microbiota-directed dietary intervention: Focusing on microbial biomarkers and host mechanisms.

Yue Xiao, Yingxuan Feng, Jianxin Zhao, Wei Chen, Wenwei Lu

State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, PR China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, PR China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, PR China. Electronic address: [email protected]. · pubmed

Paper

Abstract

Population aging has become a primary global public health issue, and the prevention of age-associated diseases and prolonging healthy life expectancies are of particular importance. Gut microbiota has emerged as a novel target in various host physiological disorders including aging. Comprehensive understanding on changes of gut microbiota during aging, in particular gut microbiota characteristics of centenarians, can provide us possibility to achieving healthy aging or intervene pathological aging through gut microbiota-directed strategies.

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Research summary

The paper claims that understanding gut microbiota changes during aging can lead to dietary interventions that promote healthy aging. This research is relevant as it addresses potential root causes of aging through the modulation of gut microbiota, which may influence age-related health outcomes.

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