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RESEARCH PAPER / 2025-07-17

A 60-Second Interpretable Voice Model for Early Dementia Screening

Mekulu, K., Aqlan, F., Yang, H.

Pennsylvania State UniversityPennsylvania State University · medrxiv

Abstract

Early detection of cognitive impairment in assisted living is hindered by time intensive tools like MMSE and MoCA. We present a 60-second voice based screening model that analyzes picture descriptions to estimate dementia risk. Using transcripts from the DementiaBank corpus, our model integrates traditional linguistic features (pause rate, pronoun use, syntactic complexity) with latent semantic dimensions extracted from language model embeddings. These semantic axes, interpretable constructs like "Drift & Hesitation" or "Over detailed Narration", consistently emerged as top predictors and may represent novel linguistic biomarkers of early decline. The final ElasticNet classifier is sparse, interpretable, and outperforms known non deep learning baselines (AUC = 0.858), exceeding MMSE. Its simplicity enables deployment in mobile apps or in-room monitors, offering scalable, low burden screening for early dementia. This work supports a shift toward linguistically grounded, tech enabled cognitive care in aging populations.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that a 60-second voice-based screening model can effectively estimate dementia risk using linguistic features. This research is relevant as it addresses early detection of cognitive impairment, which is a significant concern in aging populations and could lead to improved cognitive care strategies.

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