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RESEARCH PAPER / 2024-12-26

Community Threat, Positive Parenting, and Accelerated Epigenetic Aging: Longitudinal Links from Childhood to Adolescence

Metrailer, G., Tavares, K., Ver Pault, M., Lopez, A., Denherder, S., Hernandez Valencia, E., DiMarzio, K., Highlander, A., Merrill, S. M., Rojo-Wissar, D. M., Parent, J.

University of Rhode Island · medrxiv

Abstract

Early Life Adversity (ELA) has been linked to accelerated epigenetic aging. While positive parenting is hypothesized to buffer the detrimental effects of ELA on child development, its role in mitigating epigenetic age acceleration remains unclear. Data from 2,039 children (49.7% female) in the Future of Families and Child Wellbeing Study (FFCWS) were included in the current study (46.7% Black, 26.5% Hispanic, 19% White non-Hispanic). Home and community threat and observed parenting were measured from ages 3 to 9. Epigenetic age acceleration was measured at ages 9 and 15. Positive parenting reduces the pace of epigenetic aging in low, but not high, community-threat environments. Interventions across home and community environments may be necessary to prevent ELA's biological embedding.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper explores the relationship between early life adversity, positive parenting, and epigenetic aging, which is relevant to understanding biological aging processes. However, while it provides insights into how environmental factors may influence epigenetic age acceleration, the findings are more focused on the effects of parenting and community threats rather than addressing the root causes of aging or proposing interventions that could significantly extend lifespan or mitigate age-related diseases. Thus, the impact is solid but limited.

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